Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31384524 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2AL3MBTL1MAPK1SLC6A2 | |
| SCHEMBL8063409 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL858792 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL13533438 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL858791 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL31384571 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AL3MBTL1MAPK1SLC6A2 | |
| SCHEMBL22492382 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1MAPK1SLC6A2 | |
| SCHEMBL1516856 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1MAPK1SLC6A2 | |
| SCHEMBL13391450 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1MAPK1SLC6A2 | |
| SCHEMBL8357538 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2AL3MBTL1MAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003727-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007685-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-02-18 | — | — | WO | disclosed |