SCHEMBL8063409

SCHEMBL8063409

CSC(=NC(=O)OCc1ccccc1)NNC(=O)NC(=O)OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 1/20 0.42
CTSK P43235 4/20 0.42
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ATM Q13315 1/20 0.41
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8063735 0.90 L3MBTL1 (0.46) ALDH1A1NPC1RAB9APOLBCTSK
SCHEMBL13533438 0.90 ALDH1A1 (0.49) ALDH1A1NPC1RAB9APOLBLMNA
SCHEMBL858792 0.90 ALDH1A1 (0.49) ALDH1A1NPC1RAB9APOLBLMNA
SCHEMBL858791 0.90 ALDH1A1 (0.49) ALDH1A1NPC1RAB9APOLBLMNA
SCHEMBL8065769 0.90 SYK (0.43) ALDH1A1NPC1RAB9APOLBCTSK
SCHEMBL8058467 0.84 ALDH1A1 (0.49) ALDH1A1NPC1RAB9APOLBLMNA
SCHEMBL7761445 0.84 RAB9A (0.46) ALDH1A1NPC1RAB9APOLBLMNA
SCHEMBL7754976 0.84 RAB9A (0.46) ALDH1A1NPC1RAB9APOLBLMNA
SCHEMBL7758925 0.83 ALDH1A1 (0.47) ALDH1A1NPC1RAB9APOLBLMNA
SCHEMBL7758927 0.83 ALDH1A1 (0.47) ALDH1A1NPC1RAB9APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6162925-A Antibiotic for methicillin resistant bacteria RESEARCH CORPORATION TECH., INC. (US) 2000-12-19 US disclosed
US-6110925-A EFFECTIVE AGAINST STAPHYLOCOCCUS; ANTITUMOR AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2000-08-29 US disclosed
EP-1003727-A1 ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA RESEARCH CORPORATION TECHNOLOGIES (US) 2000-05-31 EP disclosed
WO-1999007685-A1 ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1999-02-18 WO disclosed