Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867779 | 0.76 | PTGS2 (0.51) | PTGS2 | |
| SCHEMBL8071851 | 0.74 | PTGS2 (0.39) | CA1CA2CA9PTGS2ALDH1A1 | |
| SCHEMBL8067397 | 0.73 | CA9 (0.48) | CA9MAPTLMNAMEN1KMT2A | |
| SCHEMBL8196869 | 0.71 | PTGS2 (0.42) | PTGS2CCR1RIPK2ALDH1A1MAPT | |
| SCHEMBL8953988 | 0.69 | PTGS2 (0.51) | CA1CA2CA9PTGS2 | |
| SCHEMBL8071678 | 0.68 | PTGS2 (0.46) | CA1CA2CA9PTGS2ALDH1A1 | |
| SCHEMBL7867784 | 0.68 | PTGS2 (0.51) | PTGS2 | |
| SCHEMBL7876295 | 0.66 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL8689150 | 0.66 | PTGS2 (0.47) | PTGS2MAPT | |
| SCHEMBL6341186 | 0.65 | PTGS2 (0.69) | PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017678-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015505-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | claimed |