Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069971 | 0.82 | CA9 (0.51) | CA9CHRNA7KMT2AMAPTMEN1 | |
| SCHEMBL7874475 | 0.80 | CHRNA7 (0.63) | CA9CHRNA7 | |
| SCHEMBL8071678 | 0.74 | PTGS2 (0.46) | CA9KMT2AMAPTMEN1LMNA | |
| SCHEMBL2920972 | 0.72 | KMT2A (0.52) | CA9CHRNA7KMT2AMAPTTDP1 | |
| SCHEMBL7867789 | 0.72 | CHRNA7 (0.63) | CA9CHRNA7 | |
| SCHEMBL2195298 | 0.71 | CHRNA7 (0.54) | CA9CHRNA7KMT2AMAPTTDP1 | |
| SCHEMBL1764921 | 0.71 | TP53 (0.57) | CA9CHRNA7KMT2AMAPTTDP1 | |
| SCHEMBL2195530 | 0.70 | LMNA (0.56) | CA9CHRNA7KMT2ATP53LMNA | |
| SCHEMBL8633828 | 0.70 | CA9 (0.77) | CA9CHRNA7 | |
| SCHEMBL2917636 | 0.69 | CA9 (0.48) | CA9CHRNA7KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017678-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015505-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |