Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135076 | 0.95 | ALDH1A1 (0.39) | ALDH1A1GAAADORA3ADORA2BADORA1 | |
| SCHEMBL3147248 | 0.81 | NOTUM (0.42) | GAAKMT2ALMNAPTGS2MAPT | |
| SCHEMBL7388444 | 0.76 | CHRM5 (0.37) | HRH1HPGDMAPK1CHRNB2CHRNA4 | |
| SCHEMBL16225090 | 0.76 | HPGD (0.42) | HRH1KMT2ASMN1; SMN2HTR1AHTR7 | |
| SCHEMBL7390434 | 0.74 | MEN1 (0.38) | GAAHRH1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7390084 | 0.74 | HRH1 (0.36) | ALDH1A1HRH1HTR1AHTR7HSD17B10 | |
| SCHEMBL5069314 | 0.73 | — | — | |
| SCHEMBL19405550 | 0.72 | GRM2 (0.31) | — | |
| SCHEMBL19405361 | 0.72 | TP53 (0.32) | NPSR1 | |
| SCHEMBL19405411 | 0.72 | ABCB1 (0.31) | GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034086-A | VIRICIDES; AIDS THERAPY | UBE INDUSTRIES, LTD. | 2000-03-07 | — | — | US | disclosed |