SCHEMBL5135076

SCHEMBL5135076

[c]1cccc(-c2ccccc2)c1C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
NPSR1 Q6W5P4 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTGS2 P35354 1/20 0.38
ADORA3 P0DMS8 2/20 0.38
ADORA2B P29275 2/20 0.38
ADORA1 P30542 2/20 0.38
ADORA2A P29274 1/20 0.38
POLB P06746 1/20 0.37
CASP3 P42574 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 1/20 0.36
PTPN1 P18031 2/20 0.36
PTPRC P08575 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8058587 0.95 ALDH1A1 (0.37) ALDH1A1NPSR1MEN1KMT2ALMNA
SCHEMBL3147248 0.87 NOTUM (0.42) KMT2ALMNAPTGS2TDP1GAA
SCHEMBL7390434 0.76 MEN1 (0.38) MEN1KMT2ASMN1; SMN2POLBGAA
SCHEMBL7388444 0.74 CHRM5 (0.37) HRH1
SCHEMBL16225090 0.74 HPGD (0.42) KMT2ASMN1; SMN2HRH1
SCHEMBL529103 0.74 PTGDR2 (0.36) PTGS2
SCHEMBL9644212 0.74 PTGDR2 (0.36) PTGS2
SCHEMBL1816231 0.73 SIGMAR1 (0.34) LMNAGAA
SCHEMBL436786 0.73 NPSR1 (0.33) ALDH1A1NPSR1MEN1KMT2ALMNA
SCHEMBL435185 0.73 ABCB1 (0.37) MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080171143-A1 Process For Preparation Of Optical Compensatory Sheet FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
WO-2006064950-A1 PREPARATION OF AN OPTICAL COMPENSATION SHEET USING PHOTOSENSITIVE COMPOUNDS FUJIFILM CORPORATION (JP) 2006-06-22 WO disclosed
US-6034086-A VIRICIDES; AIDS THERAPY UBE INDUSTRIES, LTD. 2000-03-07 US disclosed