SCHEMBL8058637

SCHEMBL8058637

CCCCC(C)C(=O)OC=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.44
CA2 P00918 2/20 0.41
CTSK P43235 5/20 0.39
TSHR P16473 3/20 0.39
SLC15A1 P46059 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FDPS P14324 1/20 0.38
ATM Q13315 2/20 0.37
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPK1 P28482 1/20 0.36
ACE2 Q9BYF1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3617251 0.92 CA1 (0.50) CA1FDPSACE2
SCHEMBL28198656 0.92 CA1 (0.50) CA1FDPSACE2
SCHEMBL5560875 0.88 SMN1; SMN2 (0.37) CA1CA2CTSKTSHRSMN1; SMN2
SCHEMBL27846784 0.85 FAAH (0.46) ATMCYP3A4
SCHEMBL12158831 0.82 TSHR (0.45) CA1CA2CTSKTSHRFDPS
Ethane SCHEMBL27996835 0.81 TSHR (0.44) CA1CA2CTSKTSHRFDPS
SCHEMBL28124826 0.80 GPR84 (0.44) CA1CA2CTSKTSHRSMN1; SMN2
SCHEMBL4601896 0.79 BLM (0.36) CA1TSHRTDP1
SCHEMBL5722200 0.79
SCHEMBL22773828 0.79 CA1 (0.50) CA1CA2TSHRSLC15A1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877728-B1 PROCESS FOR THE CARBONYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS SHELL INT RESEARCH (NL) 2000-04-05 EP disclosed
US-5952522-A CATALYZING THE REACTION WITH CARBON MONOXIDE AND A CO-REACTANT IN THE PRESENCE OF A CATALYST SYSTEM COMPRISING A SOURCE OF PLATINUM, A BIDENTATE LIGAND AND A SOURCE OF ANIONS SHELL OIL COMPANY (US) 1999-09-14 US disclosed
EP-0877728-A1 PROCESS FOR THE CARBONYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1998-11-18 EP disclosed
WO-1997020803-A1 PROCESS FOR THE CARBONYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1997-06-12 WO disclosed