Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24758142 | 0.80 | HCAR2 (0.37) | RETMAPK1LCKSRCDAO | |
| SCHEMBL5355374 | 0.79 | MAPK1 (0.59) | ALPLMAPK1HCAR2GAAMAPT | |
| SCHEMBL10340622 | 0.78 | HCAR2 (0.52) | DAOHCAR2MAPT | |
| SCHEMBL18236174 | 0.77 | ALPL (0.41) | BAZ2BRETPIM1GSK3BCHEK1 | |
| SCHEMBL2619220 | 0.74 | DAO (0.62) | BAZ2BALPLDAOHCAR2LMNA | |
| SCHEMBL164683 | 0.74 | BAZ2B (0.42) | BAZ2BRETPIM1GSK3BCHEK1 | |
| SCHEMBL23185764 | 0.74 | CHEK1 (0.57) | BAZ2BRETPIM1GSK3BCHEK1 | |
| SCHEMBL12694613 | 0.73 | BAZ2B (0.41) | MAPK8MAPK9BAZ2BRETPIM1 | |
| SCHEMBL24117299 | 0.72 | MAPK1 (0.39) | MAPK1HCAR2LMNAMAPTKDM4E | |
| SCHEMBL20488775 | 0.71 | CHEK1 (0.50) | RETPIM1GSK3BCHEK1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114358-A | Thrombin inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |