SCHEMBL8058718

SCHEMBL8058718

COc1ccc(Oc2cccc(C(=O)O)n2)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 3/20 0.49
PTGER1 P34995 1/20 0.49
KMO O15229 2/20 0.49
MRGPRX4 Q96LA9 2/20 0.45
HRH3 Q9Y5N1 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 1/20 0.44
GRM4 Q14833 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8069135 0.85 GRM4 (0.46) P2RX3HRH3L3MBTL1KDM4EMAPT
SCHEMBL7111276 0.81 MAPT (0.53) P2RX3PTGER1MRGPRX4L3MBTL1KDM4E
SCHEMBL28444872 0.76 KMO (0.64) KMOMRGPRX4L3MBTL1KDM4EGRM4
SCHEMBL7108378 0.76 MAPT (0.49) P2RX3PTGER1KMOMRGPRX4HRH3
SCHEMBL8629482 0.75 PTGER1 (0.49) P2RX3PTGER1KMOMRGPRX4L3MBTL1
SCHEMBL7113346 0.74 MAPT (0.45) P2RX3PTGER1KMOMRGPRX4MAPT
SCHEMBL7110101 0.74 KDM4E (0.57) P2RX3PTGER1L3MBTL1KDM4EMAPT
SCHEMBL13083700 0.74 KMT2A (0.46) KMOL3MBTL1KDM4EMAPTGRM4
SCHEMBL17338 0.74 TDP1 (0.61) L3MBTL1KDM4EPOLB
SCHEMBL29527015 0.74 TDP1 (0.61) L3MBTL1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6159901-A 6-phenoxy picolinic acid alkylidene hydrazide derivative, process for producing the same and herbicide using the same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-12-12 US disclosed
EP-1020444-A1 6-PHENOXYPICOLINIC ACID, ALKYLIDENEHYDRAZIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed