Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721109 | 0.87 | F2 (0.44) | KMOL3MBTL1GRM5PPARG | |
| SCHEMBL8633384 | 0.85 | MAPT (0.59) | L3MBTL1MRGPRX4GRM5MAPTP2RX3 | |
| SCHEMBL9017227 | 0.80 | MAPT (0.52) | KDM4EGRM5MAPT | |
| SCHEMBL13222885 | 0.79 | LMNA (0.49) | PTGER1L3MBTL1KDM4EALOX15TSHR | |
| SCHEMBL7110101 | 0.77 | KDM4E (0.57) | PTGER1L3MBTL1KDM4EALOX15TSHR | |
| SCHEMBL8627197 | 0.76 | RECQL (0.42) | L3MBTL1GRM5PPARGP2RX3 | |
| SCHEMBL9017144 | 0.75 | GRM5 (0.38) | L3MBTL1GRM5MAPT | |
| SCHEMBL8721952 | 0.75 | PTGER1 (0.44) | PTGER1GRM5PPARG | |
| SCHEMBL8058718 | 0.75 | P2RX3 (0.49) | PTGER1KMOL3MBTL1KDM4EMRGPRX4 | |
| SCHEMBL8630455 | 0.74 | L3MBTL1 (0.37) | L3MBTL1GRM5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807804-A | CONTROLLING WEEDS | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5710106-A | Substituted pyridine herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0537816-B1 | Herbicidal picolinamide derivatives | SHELL INT RESEARCH (NL) | 1996-04-24 | — | — | EP | disclosed |
| US-5371061-A | Herbicidal picolinamide derivatives | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| CN-1071425-A | Picolinamide derivatives with weeding activity | SHELL INT RESEARCH (NL) | 1993-04-28 | — | — | CN | disclosed |
| EP-0537816-A1 | Herbicidal picolinamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-04-21 | — | — | EP | disclosed |