SCHEMBL8058732

SCHEMBL8058732

O=C1CCC(C(=O)O)C(=O)C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.32
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5516725 0.80
SCHEMBL1069345 0.80
SCHEMBL2187877 0.77 MCL1 (0.62) MCL1KDM4EGAA
SCHEMBL29980746 0.76 GRM8 (0.34) KDM4EGAA
SCHEMBL28395084 0.75 ALDH1A1 (0.36) KDM4E
SCHEMBL932332 0.71
SCHEMBL22468834 0.71
SCHEMBL11305170 0.70 CYP2D6 (0.33)
SCHEMBL612494 0.70 MCL1 (0.60) MCL1KDM4E
SCHEMBL3553694 0.70 MCL1 (0.60) MCL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631208-A Herbicidal cyclohexane-1,3-dione derivatives and their preparation process KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-05-20 US claimed
WO-1996006071-A1 NOVEL HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES AND THEIR PREPARATION PROCESS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-02-29 WO claimed
US-6096930-A PREPARATION OF 2-METHYLINDANECARBOXYALDEHYDES BY REACTING A MALONYL HALIDE WITH A BENZENE DERIVATIVE, REDUCTION OF THE FORMED INDANEDIONE, REACTION WITH DICHLOROMETHYL METHYL ETHER KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2000-08-01 US disclosed
US-5631208-A Herbicidal cyclohexane-1,3-dione derivatives and their preparation process KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-05-20 US disclosed
WO-1996006071-A1 NOVEL HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES AND THEIR PREPARATION PROCESS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-02-29 WO disclosed
WO-1994003443-A1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES AND THEIR PREPARATION PROCESS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1994-02-17 WO disclosed
US-5169988-A From unsaturated methyl ketone CIBA-GEIGY CORPORATION (US) 1992-12-08 US disclosed
US-5132462-A Sulfide, sulfonyl and sulfinyl compounds, agricultural use CIBA-GEIGY CORPORATION (US) 1992-07-21 US disclosed
US-5026899-A Acylcylohexanediones and the oxime ethers thereof with herbicidal and plant growth regulating properties CIBA-GEIGY CORPORATION (US) 1991-06-25 US disclosed
US-4909835-A Containing a sulfur substitution in position 5 CIBA-GEIGY CORPORATION (US) 1990-03-20 US disclosed
US-4432378-A ORGANOLEPTIC; TOBACCO; FOODS; DETERGENTS; COSMETICS FRITZSCHE, DODGE & OLCOTT, INC. (US) 1984-02-21 US disclosed
US-4326996-A FOR PERFUMES FRITZSCHE DODGE & OLCOTT INC. (US) 1982-04-27 US disclosed
US-4281204-A ALKYLATION, DECARBOXYLATION TO CYCLIZE FRITZSCHE DODGE & OLCOTT INC. (US) 1981-07-28 US disclosed