Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14327017 | 0.89 | MTNR1A (0.42) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL1646076 | 0.89 | MTNR1B (0.39) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL4688545 | 0.84 | MTNR1B (0.39) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL338471 | 0.84 | MTNR1B (0.39) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL338470 | 0.84 | MTNR1B (0.39) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL339102 | 0.82 | MTNR1B (0.38) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL339103 | 0.82 | MTNR1B (0.38) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL793401 | 0.81 | MTNR1B (0.56) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL2881136 | 0.81 | MTNR1B (0.56) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL805922 | 0.81 | MTNR1B (0.56) | MTNR1AMTNR1BABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035303-A2 | A NOVEL PROCESS FOR SYNTHESIS OF RAMELTEON, AND KEY INTERMEDIATES FOR THE SYNTHESIS OF RAMELTEON | CIPLA LIMITED ET AL (IN) | 2012-03-22 | — | — | WO | disclosed |