Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 6/20 | 0.53 |
| ▸ | GLP1R | P43220 | 2/20 | 0.52 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | GIPR | P48546 | 1/20 | 0.52 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 5/20 | 0.50 |
| ▸ | NPY1R | P25929 | 4/20 | 0.50 |
| ▸ | NPY2R | P49146 | 4/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.50 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058915 | 1.00 | TFPI (0.54) | TFPIIL23RGLP1RGCGRGIPR | |
| SCHEMBL10428709 | 0.96 | IL23R (0.54) | TFPIIL23RGLP1RGCGRGIPR | |
| SCHEMBL10428706 | 0.96 | IL23R (0.54) | TFPIIL23RGLP1RGCGRGIPR | |
| SCHEMBL31498888 | 0.89 | TFPI (0.62) | TFPIIL23RGLP1RGCGRGIPR | |
| SCHEMBL29512407 | 0.88 | NPY4R (0.58) | TFPIIL23RVIPR2NPY4RNPY1R | |
| SCHEMBL18613838 | 0.87 | NPY4R (0.60) | IL23RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL18613835 | 0.87 | NPY4R (0.60) | IL23RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29649202 | 0.87 | IL23R (0.60) | TFPIIL23RGLP1RGCGRGIPR | |
| SCHEMBL29794100 | 0.87 | TFPI (0.67) | TFPIIL23RGLP1RGCGRGIPR | |
| SCHEMBL31182635 | 0.86 | GLP1R (0.64) | TFPIGLP1RGCGRGIPRVIPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379511-A1 | POLYPEPTIDES WITH LAMININ ACTIVITY. | UNIV MINNESOTA (US) | 1990-08-01 | — | — | EP | claimed |
| WO-1989001493-A1 | POLYPEPTIDES WITH LAMININ ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-02-23 | — | — | WO | claimed |
| EP-1003561-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SurModics, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999008717-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SURMODICS, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| EP-0379511-A1 | POLYPEPTIDES WITH LAMININ ACTIVITY. | UNIV MINNESOTA (US) | 1990-08-01 | — | — | EP | disclosed |
| WO-1989001493-A1 | POLYPEPTIDES WITH LAMININ ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-02-23 | — | — | WO | disclosed |