SCHEMBL10428709

SCHEMBL10428709

CSCC[C@H](NC(=O)CNC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C)[C@@H](C)O

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 5/20 0.54
▸ GLP1R P43220 2/20 0.54
▸ GCGR P47871 1/20 0.54
▸ GIPR P48546 1/20 0.54
▸ KEAP1 Q14145 1/20 0.52
▸ NPY4R P50391 5/20 0.52
▸ NPY1R P25929 4/20 0.52
▸ NPY2R P49146 4/20 0.52
▸ NPY5R Q15761 4/20 0.52
▸ TFPI P10646 1/20 0.51
▸ VIPR2 P41587 2/20 0.51
▸ CCKBR P32239 1/20 0.50
▸ VIPR1 P32241 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10428706 1.00 IL23R (0.54) IL23RGLP1RGCGRGIPRKEAP1
SCHEMBL8058908 0.96 TFPI (0.54) IL23RGLP1RGCGRGIPRNPY4R
SCHEMBL8058915 0.96 TFPI (0.54) IL23RGLP1RGCGRGIPRNPY4R
SCHEMBL29512407 0.92 NPY4R (0.58) IL23RKEAP1NPY4RNPY1RNPY2R
SCHEMBL29611531 0.88 NPY4R (0.64) IL23RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29816829 0.88 GLP1R (0.50) IL23RGLP1RGCGRGIPRNPY4R
SCHEMBL16976144 0.87 NPY4R (0.60) IL23RKEAP1NPY4RNPY1RNPY2R
SCHEMBL18613838 0.87 NPY4R (0.60) IL23RNPY4RNPY1RNPY2RNPY5R
SCHEMBL18613835 0.87 NPY4R (0.60) IL23RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29777861 0.87 TFPI (0.62) IL23RNPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379511-A1 POLYPEPTIDES WITH LAMININ ACTIVITY. UNIV MINNESOTA (US) 1990-08-01 — — EP claimed
WO-1989001493-A1 POLYPEPTIDES WITH LAMININ ACTIVITY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1989-02-23 — — WO claimed
Send feedback