Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879861 | 1.00 | PIK3CD (0.34) | PIK3CDPIK3R1 | |
| SCHEMBL15315382 | 0.90 | — | — | |
| SCHEMBL12879581 | 0.90 | — | — | |
| SCHEMBL1203055 | 0.90 | DRD2 (0.31) | — | |
| SCHEMBL12879870 | 0.90 | DRD2 (0.31) | — | |
| SCHEMBL15317965 | 0.88 | ADAMTS5 (0.31) | PIK3R1 | |
| SCHEMBL8036900 | 0.84 | PTPN11 (0.34) | PIK3CDPIK3R1 | |
| SCHEMBL12879784 | 0.84 | DRD3 (0.32) | — | |
| SCHEMBL12879850 | 0.84 | — | — | |
| SCHEMBL12879558 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050236-A1 | NOVEL PIPERAZINO-DIHYDROTHIENOPYRIMIDINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |