Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069997 | 0.90 | KDM4E (0.32) | BCHEACHE | |
| SCHEMBL8059237 | 0.85 | DRD2 (0.30) | — | |
| SCHEMBL8059301 | 0.85 | CA1 (0.33) | — | |
| SCHEMBL8070430 | 0.80 | PARP1 (0.36) | — | |
| SCHEMBL8059334 | 0.76 | NLRP3 (0.31) | — | |
| SCHEMBL8059305 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL8070580 | 0.75 | MEN1 (0.32) | — | |
| SCHEMBL8069998 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL8068400 | 0.73 | — | — | |
| SCHEMBL8070377 | 0.73 | BRD4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803501-B1 | Substituted guanidine derivatives and their use as Na+/H+ exchange inhibitors | SUMITOMO PHARMA (JP) | 2000-07-05 | — | — | EP | disclosed |
| EP-0803501-A1 | Substituted guanidine derivatives and their use as Na+/H+ exchange inhibitors | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-29 | — | — | EP | disclosed |