Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285317 | 1.00 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL10695813 | 0.92 | ALDH1A1 (0.49) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL10758017 | 0.85 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL10354380 | 0.85 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL28605251 | 0.84 | TSHR (0.43) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL28014703 | 0.83 | ALDH1A1 (0.58) | ALDH1A1POLBSMN1; SMN2KDM4EHTT | |
| SCHEMBL10691786 | 0.82 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL16247255 | 0.81 | ALDH1A1 (0.37) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL120994 | 0.80 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL29414916 | 0.80 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| CN-115840013-B | Method for detecting 3-chloro-2-fluoro-5- (trifluoromethyl) pyridine in soil and water by using gas chromatography | 贵州健安德科技有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119751343-A | Fluopicola strain Process for the preparation of amides | 天津均凯农业科技有限公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| CN-116924973-A | Preparation method of 3-chloro-2-aminomethyl-5-trifluoromethyl pyridine hydrochloride | 天津均凯农业科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116003314-A | Method for purifying 2-fluoro-3-chloro-5-trifluoromethyl pyridine by utilizing microreactor | 内蒙古佳瑞米精细化工有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-115840013-A | Method for detecting 3-chloro-2-fluoro-5- (trifluoromethyl) pyridine in soil and water by using gas chromatography | 贵州健安德科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-112390747-A | Combined preparation method of 2-cyano-3-chloro-5-trifluoromethylpyridine and succinonitrile | 内蒙古佳瑞米精细化工有限公司 | 2021-02-23 | — | — | CN | claimed |
| CN-107286087-B | Synthetic method of 2-cyano-3-chloro-5-trifluoromethylpyridine | 内蒙古佳瑞米精细化工有限公司 | 2020-01-07 | — | — | CN | claimed |
| CN-110143916-A | A kind of synthesis technology of fluazinam | 大连九信精细化工有限公司 | 2019-08-20 | — | — | CN | claimed |
| US-4547577-A | Preparation of (trifluoromethyl)pyridines | THE DOW CHEMICAL COMPANY (US) | 1985-10-15 | — | — | US | claimed |
| US-4546192-A | Chlorine exchange for fluorine in ring-fluorinated pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-10-08 | — | — | US | claimed |
| EP-0063872-B1 | PROCESS FOR THE PREPARATION OF FLUOROMETHYL PYRIDINES AND CERTAIN NOVEL PRODUCTS OBTAINED THEREFROM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-17 | — | — | EP | claimed |
| EP-0146924-A2 | Preparation of difluorpyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-07-03 | — | — | EP | claimed |
| US-4493932-A | Chlorine exchange for fluorine in 2-fluoro-pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-01-15 | — | — | US | claimed |
| US-4490534-A | CHLORINATION IN VAPOR PHASE, PRESENCE OF CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-12-25 | — | — | US | claimed |
| US-4480102-A | 2,3-Difluoro-5-(trifluoromethyl)pyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1984-10-30 | — | — | US | claimed |
| EP-0104715-A2 | 2,3-Difluoro-5-(trifluoromethyl)pyridine and method of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1984-04-04 | — | — | EP | claimed |
| EP-0078410-A2 | Process for producing 3-chloro-5-trifluoromethylpyridines | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-05-11 | — | — | EP | claimed |
| EP-0063872-A1 | Process for the preparation of fluoromethyl pyridines and certain novel products obtained therefrom | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-03 | — | — | EP | claimed |