Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805963 | 0.92 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL30285317 | 0.92 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL10691786 | 0.89 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL609041 | 0.88 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL10758017 | 0.79 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL10354380 | 0.79 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL9256577 | 0.78 | BACE1 (0.32) | — | |
| SCHEMBL28605251 | 0.78 | TSHR (0.43) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU | |
| SCHEMBL28014703 | 0.77 | ALDH1A1 (0.58) | ALDH1A1POLBSMN1; SMN2KDM4EHTT | |
| SCHEMBL30062543 | 0.76 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2KDM4EPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782161-A | HALOGEN EXCHANGE, ACTIVATED CARBON CATALYST | THE DOW CHEMICAL COMPANY (US) | 1988-11-01 | — | — | US | disclosed |