SCHEMBL8059787

SCHEMBL8059787

Nc1ccc2c(O)c(N=Nc3ccc4c(S(=O)(=O)O)cccc4c3S(=O)(=O)O)c(S(=O)(=O)O)cc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 2/20 0.60
ENPP2 Q13822 4/20 0.53
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ATIC P31939 2/20 0.48
SUMO2 P61956 1/20 0.48
SUMO1 P63165 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP2 Q9HC62 1/20 0.48
CYP1A2 P05177 4/20 0.48
MPL P40238 1/20 0.46
CTRC Q99895 1/20 0.46
ALDH1A1 P00352 1/20 0.45
HIF1A Q16665 1/20 0.45
CTRB1 P17538 1/20 0.45
CD40 P25942 1/20 0.44
CD40LG P29965 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9300854 1.00 PHLPP2 (0.60) PHLPP2ENPP2MEN1THRBKMT2A
Ammonia Solution, Strong SCHEMBL10651283 0.89 CYP1A2 (0.55) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL10351683 0.88 ENPP2 (0.50) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL10351681 0.88 ENPP2 (0.50) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL14645033 0.88 PHLPP2 (0.64) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL10351831 0.87 MEN1 (0.50) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL8533049 0.87 MEN1 (0.50) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL13763549 0.87 ALDH1A1 (0.52) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL10618181 0.85 ENPP2 (0.64) PHLPP2ENPP2MEN1THRBKMT2A
SCHEMBL9310020 0.85 CYP1A2 (0.51) PHLPP2ENPP2MEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4772323-A IMPROVED STORAGE AND EJECTION STABILITY CANON KABUSHIKI KAISHA (JP) 1988-09-20 US claimed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0694053-B1 WATER-SOLUBLE FIBER-REACTIVE DYES, PROCESS FOR PRODUCING THE SAME AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO (DE) 1998-07-22 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
US-5399674-A Dyestuffs containing pyrimidine-carboxylic acid amide radical having fiber-reactive group, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-21 US disclosed
EP-0624630-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-17 EP disclosed
US-5359043-A Reactive dyes having a sulphonamido group ZENECA LIMITED (GB) 1994-10-25 US disclosed
EP-0603595-A1 Fibre reactive dyes, method for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0167219-A1 Fiber-reactive compound having both pyridiniotriazinyl and vinylsulfone type groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-08 EP disclosed
US-4507236-A Fibre-reactive dyes, containing both chloro and fluoro triazine radicals CIBA-GEIGY CORPORATION (US) 1985-03-26 US disclosed
EP-0059355-A2 Use of reactive dyestuffs in dyeing and printing of hydroxylgroups containing fibrous materials BAYER AG (DE) 1982-09-08 EP disclosed
US-4325869-A CONTAINING A PYRIMIDINE RING AND ONE OR MORE AZO GROUPS CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed
US-4263206-A Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-04-21 US disclosed
US-4261889-A TRIAZINE DYES FOR COTTON CIBA-GEIGY CORP. (US) 1981-04-14 US disclosed
US-4213899-A FOR CELLULOSE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-22 US disclosed
US-4129736-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1978-12-12 US disclosed
US-4079051-A 4-Halogeno-s-triazin-2-yl-phosphoramide acid containing reactive dyestuffs CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed
US-4033944-A Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 US disclosed