SCHEMBL8059977

SCHEMBL8059977

[NH]c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
HSD17B10 Q99714 5/20 0.53
CYP2A6 P11509 4/20 0.53
TSHR P16473 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
CYP1A2 P05177 5/20 0.48
HPGD P15428 3/20 0.48
CYP3A4 P08684 2/20 0.48
KEAP1 Q14145 1/20 0.48
HPRT1 P00492 1/20 0.48
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
THRB P10828 1/20 0.43
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
SIGMAR1 Q99720 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49402 1.00 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL131747 0.85 HPRT1 (0.67) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL3787727 0.81 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL2007783 0.79 HSD17B10 (0.54) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL241836 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL8014875 0.72 CYP2A6 (0.55) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL6350288 0.72 CYP2A6 (0.55) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL4377802 0.70 ALDH1A1 (0.85) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Phenanthrene SCHEMBL30932938 0.70 CYP2A6 (1.00) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Phenanthrene SCHEMBL7643 0.70 CYP2A6 (1.00) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390608-B1 LIQUID DETERGENTS OR CLEANING AGENTS CONTAINING ACYL HYDRAZONE HENKEL AG & CO KGAA (DE) 2021-07-07 EP claimed
EP-3143115-B1 WASHING AND CLEANING AGENT WITH ENHANCED BLEACHING PERFORMANCE HENKEL AG & CO KGAA (DE) 2020-02-19 EP claimed
EP-3221441-B1 WATER-SOLUBLE PACKAGED UNIT DOSE DETERGENT COMPOSITION HENKEL AG & CO KGAA (DE) 2019-08-07 EP claimed
US-20180298309-A1 LIQUID DETERGENTS OR CLEANING AGENTS CONTAINING ACYL HYDRAZONE AND REDUCING AGENTS HENKEL AG & CO. KGAA (DE) 2018-10-18 US claimed
EP-3030642-B1 WASHING AGENT HAVING INCREASED PRIMARY WASHING EFFICIENCY HENKEL AG & CO KGAA (DE) 2018-09-05 EP claimed
EP-2912156-B1 USE OF ACYL HYDRAZONE IN DETERGENT COMPOSITIONS HENKEL AG & CO KGAA (DE) 2018-08-29 EP claimed
US-20170306267-A1 METHOD FOR WASHING TEXTILES IN A WASHING MACHINE COMPRISING AN ACTIVATION DEVICE HENKEL AG & CO. KGAA (DE) 2017-10-26 US claimed
CN-103328455-A Bleaching catalyst BASF SE 2013-09-25 CN claimed
CN-1711347-B Use of metal complex compounds as oxidation catalysts CIBA SC HOLDING AG 2010-05-26 CN claimed
CN-100567471-C Use of metal complexes as oxidation catalysts CIBA SC HOLDING AG (CH) 2009-12-09 CN claimed
CN-1898372-A Use of metal complex compounds as oxidation catalysts RECKITT BENCKISER NV (NL) 2007-01-17 CN claimed
CN-1711347-A Use of metal complex compounds as oxidation catalysts CIBA SC HOLDING AG (CH) 2005-12-21 CN claimed
CN-1708579-A Use of metal complexes as catalysts for oxidation with molecular oxygen or air CIBA SC HOLDING AG (CH) 2005-12-14 CN claimed
CN-1668730-A Use of metal complex compounds as oxidation catalysts CIBA SC HOLDING AG (CH) 2005-09-14 CN claimed
CN-1646672-A Use of metal complex compounds as oxidation catalysts CIBA SC HOLDING AG (CH) 2005-07-27 CN claimed
US-5725998-A Process for developing black-and-white silver halide photographic light-sensitive materials containing a hydrazine compound and a nucleation compound, in a developer containing a developing agent and a mercapto compound KONICA CORPORATION (JP) 1998-03-10 US claimed
US-5208341-A Pressure sensitive copying; thermoreactive or electrochromic recording materials BAYER AKTIENGESELLSCHAFT (DE) 1993-05-04 US claimed
EP-0261079-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1991-10-16 EP claimed
EP-0315433-A2 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics A.H. ROBINS COMPANY, INCORPORATED (US) 1989-05-10 EP claimed
US-4270918-A METALLIZED TRIAZINE-FUNCTIONAL MONOAZO DYE CIBA-GEIGY CORPORATION (US) 1981-06-02 US claimed