Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042358 | 0.83 | PDK1 (0.44) | OPRD1OPRK1CYP2D6CYP3A4GPR119 | |
| SCHEMBL31066454 | 0.82 | OPRD1 (0.52) | OPRD1OPRK1CYP2D6ALDH1A1GPR119 | |
| SCHEMBL27225672 | 0.82 | PDK1 (0.48) | OPRD1OPRK1STSTACR1 | |
| SCHEMBL27477846 | 0.82 | CYP2D6 (0.62) | OPRD1OPRK1CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL8060461 | 0.81 | CYP2D6 (0.67) | OPRD1OPRK1CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL31066302 | 0.80 | OPRD1 (0.41) | OPRD1OPRK1GPR119STSKDM4E | |
| SCHEMBL31066510 | 0.80 | OPRD1 (0.41) | OPRD1OPRK1GPR119STSKDM4E | |
| SCHEMBL12526355 | 0.80 | CYP2D6 (0.69) | OPRD1OPRK1CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL17793379 | 0.78 | STS (0.55) | OPRD1OPRK1GPR119STSKDM4E | |
| SCHEMBL19468922 | 0.78 | STS (0.55) | OPRD1OPRK1GPR119STSKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140333-A | FOR TREATMENT AND/OR PROPHYLAXIS OF DISEASES INCLUDE SUCH RESPIRATORY DISEASES AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CHRONIC BRONCHITIS, ASTHMA, CHRONIC RESPIRATORY OBSTRUCTION, PULMONARY FIBROSIS, PULMONARY EMPHYSEMA | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-10-31 | — | — | US | disclosed |