Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037898 | 0.87 | LMNA (0.49) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7031426 | 0.83 | LMNA (0.53) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7036099 | 0.83 | LMNA (0.53) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7031428 | 0.83 | LMNA (0.53) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7036097 | 0.83 | LMNA (0.53) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7033732 | 0.73 | SSTR3 (0.55) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7029511 | 0.72 | LMNA (0.51) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7029506 | 0.72 | LMNA (0.51) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7035598 | 0.72 | LMNA (0.50) | LMNAMAPTSSTR3TAS1R3TAS1R1 | |
| SCHEMBL7108284 | 0.72 | LMNA (0.50) | LMNAMAPTSSTR3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003714-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-05-31 | — | — | EP | claimed |
| WO-1999001422-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1999-01-14 | — | — | WO | claimed |