SCHEMBL7036099

SCHEMBL7036099

Cc1ccccc1NC(=O)c1ccc(CC=C(Cl)c2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
TAS1R2 Q8TE23 1/20 0.51
MAPT P10636 4/20 0.49
HPGD P15428 2/20 0.49
POLB P06746 1/20 0.49
SSTR3 P32745 1/20 0.48
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HTT P42858 1/20 0.46
TP53 P04637 1/20 0.45
THRB P10828 1/20 0.45
S1PR4 O95977 1/20 0.45
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036097 1.00 LMNA (0.53) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL7031426 0.89 LMNA (0.53) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL7031428 0.89 LMNA (0.53) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL7029511 0.87 LMNA (0.51) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL7029506 0.87 LMNA (0.51) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL8060671 0.83 LMNA (0.39) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL8914972 0.82 LMNA (0.69) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL7035752 0.81 LMNA (0.52) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL7035753 0.81 LMNA (0.52) LMNATAS1R3TAS1R1TAS1R2MAPT
SCHEMBL7037306 0.80 LMNA (0.55) LMNATAS1R3TAS1R1TAS1R2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides HOECHST SCHERING AGREVO S.A. (FR) 2003-12-04 US claimed
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 2002-06-06 US claimed
EP-1003714-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 2000-05-31 EP claimed
WO-1999001422-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1999-01-14 WO claimed
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides HOECHST SCHERING AGREVO S.A. (FR) 2003-12-04 US disclosed
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 2002-06-06 US disclosed
EP-1003714-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 2000-05-31 EP disclosed
WO-1999001422-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1999-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES CBR1, CBR3, CYP2E1 LMNA 1663/4885TAS1R3 2807/4885TAS1R1 2496/4885
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides CBR3, CBR1, CYP2E1 LMNA 1581/4885TAS1R3 1558/4885TAS1R1 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.