SCHEMBL8060780

SCHEMBL8060780

CNc1cc(N)cc(-c2ccn(C)c2)c1CCO

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.31
PIK3CG P48736 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7459952 0.85
SCHEMBL7459401 0.83
SCHEMBL7466693 0.78
SCHEMBL7462747 0.77 PIK3CD (0.31) PIK3CDPIK3CG
SCHEMBL7807398 0.77 ADRA1D (0.31)
SCHEMBL7459383 0.75 CSNK2A1 (0.33)
SCHEMBL7460891 0.75 CYP2A6 (0.36)
SCHEMBL7462594 0.75 PRKCI (0.32) PIK3CDPIK3CG
SCHEMBL7460027 0.71 CYP2C19 (0.32) PIK3CDPIK3CG
SCHEMBL7812179 0.70 LTA4H (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6132475-A FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS WELLA AKTIENGESELLSCHAFT (DE) 2000-10-17 US disclosed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP disclosed