SCHEMBL8060796

SCHEMBL8060796

Oc1cc(Cl)c(-c2c(Cl)cc(O)cc2Cl)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 9/20 0.65
HPGD P15428 6/20 0.65
CYP3A4 P08684 4/20 0.65
CRHBP P24387 1/20 0.65
CRHR2 Q13324 1/20 0.65
TSHR P16473 6/20 0.56
ALDH1A1 P00352 3/20 0.56
RECQL P46063 2/20 0.56
TTR P02766 3/20 0.47
CASP1 P29466 2/20 0.47
BACE1 P56817 1/20 0.47
ALOX15 P16050 3/20 0.43
THRB P10828 2/20 0.43
MAPK1 P28482 2/20 0.43
CHRM1 P11229 2/20 0.43
TBXA2R P21731 2/20 0.43
ADRA1A P35348 2/20 0.43
HTR2B P41595 2/20 0.43
MAOA P21397 1/20 0.43
ALOX12 P18054 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1902290 0.88 HSD17B10 (0.60) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL70463 0.86 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL2574718 0.86 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL330705 0.79 HSD17B10 (1.00) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL12804729 0.78 HSD17B10 (0.55) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL9623395 0.78 ABL1 (0.50) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL21839932 0.76 HSD17B10 (0.61) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL11717548 0.76 ESR2 (0.48) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL9623591 0.76 ESR1 (0.57) HSD17B10HPGDCYP3A4CRHBPCRHR2
Methoxymethane SCHEMBL8720647 0.76 HSD17B10 (0.52) HSD17B10HPGDCYP3A4CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863926-B1 A PROCESS FOR THE PRODUCTION OF CYANATE ESTER RESINS HAVING UNIQUE COMPOSITION ALLIED SIGNAL INC (US) 2000-07-26 EP disclosed
US-6045906-A PRODUCED BY FORMING A CARBON FIBER TOW, FORMING A THERMOPLASTIC POLYMERIC FIBER TOW, INTERMIXING THE TWO TOWS, AND WITHDRAWING THE INTERMIXED TOW FOR FURTHER USE CYTEC TECHNOLOGY CORP. (US) 2000-04-04 US disclosed
US-5756592-A FROM PHENOLIC RESINS ALLIEDSIGNAL, INC. (US) 1998-05-26 US disclosed
US-5157105-A Heat curable; thermosetting resins with improved toughness SHELL OIL COMPANY (US) 1992-10-20 US disclosed
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
EP-0143988-B1 PROCESSES FOR PREPARING HYDROXYAROMATIC OLIGOMERS CONTAINING TRIAZINE GROUPS AND FOR PREPARING EPOXY RESINS FROM THE OLIGOMERS THE DOW CHEMICAL COMPANY (US) 1991-09-25 EP disclosed
US-4874563-A OF CARBON FIBERS AND THERMOPLASTIC RESIN BASF STRUCTURAL MATERIALS INC. (US) 1989-10-17 US disclosed
US-4871491-A FORMING CONTINUOUS TOW OF CARBON FIBERS, FORMING CONTINUOUS TOW OF THERMOPLASTIC RESIN FIBERS, SPREADING, INTERMIXING, MOLDING BASF STRUCTURAL MATERIALS INC. (US) 1989-10-03 US disclosed
US-4818318-A Method of forming composite fiber blends HOECHST CELANESE CORP. (US) 1989-04-04 US disclosed
EP-0156959-B1 A PROCESS FOR PREPARING VINYL ESTER RESINS CONTAINING TRIAZINE OR BOTH TRIAZINE AND OXAZOLINE GROUPS THE DOW CHEMICAL COMPANY (US) 1989-01-25 EP disclosed
EP-0143988-A2 Processes for preparing hydroxyaromatic oligomers containing triazine groups and for preparing epoxy resins from the oligomers THE DOW CHEMICAL COMPANY (US) 1985-06-12 EP disclosed
WO-1985001943-A1 PROCESSES FOR PREPARING HYDROXYAROMATIC OLIGOMERS CONTAINING TRIAZINE GROUPS AND FOR PREPARING EPOXY RESINS FROM THE OLIGOMERS THE DOW CHEMICAL COMPANY (US) 1985-05-09 WO disclosed
US-4515934-A COATINGS, CASTINGS THE DOW CHEMICAL COMPANY (US) 1985-05-07 US disclosed
US-4506063-A HEAT RESISTANCE; ELONGATION THE DOW CHEMICAL COMPANY (US) 1985-03-19 US disclosed
US-4489202-A TRIMERIZATION OF A CYANATED DIHYDRIC CARBOALCOHOL; HEAT RESISTANT CASTINGS THE DOW CHEMICAL COMPANY (US) 1984-12-18 US disclosed
US-4487915-A CASTINGS, COATINGS, LAMINATION THE DOW CHEMICAL COMPANY (US) 1984-12-11 US disclosed
US-4366171-A Fungicidal biphenyl esters, mixtures thereof and method of use GAF CORPORATION (US) 1982-12-28 US disclosed
US-4247514-A AROMATIC POLYESTER, HEATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-27 US disclosed
US-4183895-A INCREASING TENSILE STRENGTH OF ORIENTED FIBERS BY HEAT TREATMENT IN RELAXED CONDITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-01-15 US disclosed
US-4049630-A Process for preparation of s-triazine prepolymers BAYER AKTIENGESELLSCHAFT (DT) 1977-09-20 US disclosed