SCHEMBL70463

SCHEMBL70463

Oc1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 9/20 0.65
HPGD P15428 6/20 0.65
TSHR P16473 6/20 0.65
CYP3A4 P08684 5/20 0.65
TTR P02766 4/20 0.65
RECQL P46063 3/20 0.65
ALDH1A1 P00352 2/20 0.65
CRHBP P24387 1/20 0.65
CRHR2 Q13324 1/20 0.65
THRB P10828 3/20 0.58
ALOX15 P16050 4/20 0.55
ALOX12 P18054 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
HIF1A Q16665 3/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
CYP2C9 P11712 1/20 0.55
MAPK1 P28482 3/20 0.50
CASP1 P29466 2/20 0.47
BACE1 P56817 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2574718 1.00 HSD17B10 (0.65) HSD17B10HPGDTSHRCYP3A4TTR
Methoxymethane SCHEMBL8720647 0.88 HSD17B10 (0.52) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL8060796 0.86 HSD17B10 (0.65) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL12804729 0.84 HSD17B10 (0.55) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL3788864 0.80 CYP3A4 (0.59) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL330705 0.79 HSD17B10 (1.00) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL463718 0.79 TTR (1.00) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL8872103 0.79 HSD17B10 (1.00) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL184648 0.79 HSD17B10 (1.00) HSD17B10HPGDTSHRCYP3A4TTR
SCHEMBL9579920 0.76 HSD17B10 (0.46) HSD17B10HPGDTSHRCYP3A4TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-110698858-B High boronizing activity polyarylene sulfide composite material with nuclear radiation protection function and preparation thereof 四川大学 2020-09-15 CN claimed
CN-110724263-B Boron-containing two-dimensional polyarylene sulfide material with neutron absorption function and preparation method thereof 四川大学 2020-08-14 CN claimed
CN-110564154-B Bonded polyarylene sulfide metal composite material with nuclear radiation protection function and preparation method thereof 四川大学 2020-07-31 CN claimed
CN-110724263-A Boron-containing two-dimensional polyarylene sulfide material with neutron absorption function and preparation method thereof 四川大学 2020-01-24 CN claimed
CN-110698858-A High boronizing activity polyarylene sulfide composite material with nuclear radiation protection function and preparation thereof 四川大学 2020-01-17 CN claimed
CN-110564154-A bonded polyarylene sulfide metal composite material with nuclear radiation protection function and preparation method thereof 四川大学 2019-12-13 CN claimed
US-20110015108-A1 Aqueous Buffered Fluoride-Containing Etch Residue Removers and Cleaners AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-01-20 US claimed
US-7807613-B2 Aqueous buffered fluoride-containing etch residue removers and cleaners AIR PRODUCTS AND CHEMICALS, INC. (US) 2010-10-05 US claimed
EP-1865915-A1 ANTIMICROBIAL AGENTS Syntopix limited (GB) 2007-12-19 EP claimed
WO-2006100496-A1 ANTIMICROBIAL AGENTS SYNTOPIX LIMITED (GB) 2006-09-28 WO claimed
US-20040266637-A1 Aqueous buffered fluoride-containing etch residue removers and cleaners VERSUM MATERIALS US, LLC 2004-12-30 US claimed
US-6083671-A EQUIDENSITY IMAGES ON A BLACK-AND-WHITE, SILVER HALIDE FILM, HALOGEN-SUBSTITUTED HYDROQUINONE AS A DEVELOPING AGENT, SULFITE AS AN ANTIOXIDANT AND PRESERVATIVE, BORATE AS A BUFFER, THIOUREA AS A ?CHEMICAL SOLARIZER?. YUROW HARVEY WARREN (US) 2000-07-04 US claimed
EP-0092617-B1 AROMATIC POLYESTER AND FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-22 EP claimed
US-4487975-A Etherification of phenols RHONE-POULENC INDUSTRIES (FR) 1984-12-11 US claimed
EP-0092617-A1 Aromatic polyester and filaments E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-02 EP claimed
US-4347349-A FROM CHLORO- OR METHYLHYDROQUINONE, TEREPHTHALIC ACID, 6-HYDROXY-2-NAPHTHOIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-08-31 US claimed
EP-4716531-A2 HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS Board of Regents, The University of Texas System (US) 2026-04-01 EP disclosed
US-4075262-A Copolyesters capable of forming an anisotropic melt E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-02-21 US disclosed
US-4066708-A PROCESS FOR PREPARING CHLORINATED HYDROQUINONE DIMETHYL ETHERS HOECHST AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed