SCHEMBL330705

SCHEMBL330705

Oc1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 1.00
HPGD P15428 7/20 1.00
CYP3A4 P08684 5/20 1.00
CRHBP P24387 1/20 1.00
CRHR2 Q13324 1/20 1.00
TSHR P16473 6/20 0.56
CASP1 P29466 1/20 0.56
ALDH1A1 P00352 2/20 0.53
HSP90AA1 P07900 2/20 0.50
MAPK1 P28482 2/20 0.50
CHRM1 P11229 2/20 0.50
ALOX15 P16050 2/20 0.50
TBXA2R P21731 2/20 0.50
ADRA1A P35348 2/20 0.50
HTR2B P41595 2/20 0.50
MAOA P21397 1/20 0.50
BACE1 P56817 1/20 0.47
TTR P02766 2/20 0.42
AKR1B1 P15121 1/20 0.42
HTR3E A5X5Y0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7785639 0.84 HSD17B10 (0.72) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL30505597 0.80 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL21625858 0.80 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL11714372 0.80 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL29745613 0.80 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL6800963 0.80 CYP3A4 (0.75) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL2574718 0.79 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL70463 0.79 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL8060796 0.79 HSD17B10 (0.65) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL69281 0.78 HSD17B10 (0.62) HSD17B10HPGDCYP3A4CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120121751-A Method for detecting chlorophenols in waste gas and application thereof 华电莱州发电有限公司 2025-06-10 CN claimed
US-11801325-B2 Tissue-adhesive polymers POLYGANICS IP B.V. (NL) 2023-10-31 US claimed
CN-115677964-A Polyurea component A and preparation method thereof, and polyurea containing component A and preparation method thereof 山东一诺威新材料有限公司 2023-02-03 CN claimed
CN-110050118-B Emissions control during catalyst regeneration 孟山都技术公司 2022-08-19 CN claimed
EP-3687588-B1 TISSUE-ADHESIVE SEALANT DEVICE POLYGANICS IP B V (NL) 2022-07-20 EP claimed
US-11160900-B2 Tissue-adhesive sealant device POLYGANICS IP B.V. (NL) 2021-11-02 US claimed
US-11065611-B2 Emission control during catalyst regeneration MONSANTO TECHNOLOGY LLC (US) 2021-07-20 US claimed
US-20200282103-A1 Tissue-Adhesive Polymers POLYGANICS IP B.V. (NL) 2020-09-10 US claimed
CN-106752080-B Disperse dye composition and preparation method and application thereof 浙江闰土研究院有限公司 2020-09-01 CN claimed
US-20200261615-A1 Tissue-Adhesive Sealant Device POLYGANICS IP B.V. (NL) 2020-08-20 US claimed
US-7807613-B2 Aqueous buffered fluoride-containing etch residue removers and cleaners AIR PRODUCTS AND CHEMICALS, INC. (US) 2010-10-05 US claimed
EP-1919597-A4 COMPOSITE MEMBRANES AND METHODS FOR THEIR PREPARATION UNIV BEN GURION (IL) 2008-08-20 EP claimed
EP-1919597-A2 COMPOSITE MEMBRANES AND METHODS FOR THEIR PREPARATION Ben Gurion University of the Negev Research and Development Authority Ltd. (IL) 2008-05-14 EP claimed
WO-2007007343-A2 COMPOSITE MEMBRANES AND METHODS FOR THEIR PREPARATION BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2007-01-18 WO claimed
US-20040266637-A1 Aqueous buffered fluoride-containing etch residue removers and cleaners VERSUM MATERIALS US, LLC 2004-12-30 US claimed
EP-0941137-B1 DECOMPOSITION OF HALOGENATED HYDROCARBONS BY HALOPHILIC ARCHAE BACTERIA PATZELT HEIKO (DE) 2001-08-08 EP claimed
US-5464771-A Cultures for degradation of pentachlorophenol using yeasts and lactic acid THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1995-11-07 US claimed
US-4410738-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
US-4410737-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
US-4410739-A LEWIS ACID, NOBLE METAL CATALYST RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11065611-B2 Emission control during catalyst regeneration CYCS, EXOC4, CPNE4 HSD17B10 1992/4885HPGD 3532/4885CYP3A4 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.