Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3673299 | 0.90 | ALDH1A1 (0.63) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL10706332 | 0.84 | ALDH1A1 (0.54) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL10706925 | 0.84 | ALDH1A1 (0.54) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL11410649 | 0.84 | ALDH1A1 (0.54) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL11418172 | 0.84 | ALDH1A1 (0.54) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL4171219 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL1318063 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL1848291 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| Hydrochloric Acid SCHEMBL10836397 | 0.81 | ALDH1A1 (0.55) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL8069918 | 0.81 | ALDH1A1 (0.62) | ALDH1A1ALOX12LMNATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780358-A1 | A process for the resolution of 6-methoxy-alpha-methyl-2-naphthaleneacetic racemic acid into its enantiomers | FARCHEMIA S.r.l. (IT) | 1997-06-25 | — | — | EP | claimed |
| EP-0780358-B1 | A process for the resolution of 6-methoxy-alpha-methyl-2-naphthaleneacetic racemic acid into its enantiomers | FARCHEMIA SRL (IT) | 2000-07-19 | — | — | EP | disclosed |
| US-5760287-A | Process for the resolution of 6-methoxy-alpha-methyl-2-naphthaleneacetic racemic acid into its enantiomers | FARCHEMIA S.R.L. (IT) | 1998-06-02 | — | — | US | disclosed |
| EP-0780358-A1 | A process for the resolution of 6-methoxy-alpha-methyl-2-naphthaleneacetic racemic acid into its enantiomers | FARCHEMIA S.r.l. (IT) | 1997-06-25 | — | — | EP | disclosed |