Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318063 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX12SIGMAR1LMNAKDM4E | |
| SCHEMBL4171219 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX12SIGMAR1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL10836397 | 0.98 | ALDH1A1 (0.55) | ALDH1A1ALOX12SIGMAR1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3673299 | 0.88 | ALDH1A1 (0.63) | ALDH1A1ALOX12LMNAKDM4ECNR1 | |
| SCHEMBL4441100 | 0.88 | IDO1 (0.50) | ALDH1A1ALOX12SIGMAR1TDP1SMN1; SMN2 | |
| SCHEMBL9063683 | 0.88 | SIGMAR1 (0.55) | ALDH1A1SIGMAR1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL1851333 | 0.85 | SIGMAR1 (0.46) | ALDH1A1ALOX12SIGMAR1POLBTHRB | |
| SCHEMBL26180478 | 0.85 | SIGMAR1 (0.46) | ALDH1A1ALOX12SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL12138912 | 0.85 | SIGMAR1 (0.46) | ALDH1A1ALOX12SIGMAR1POLBTHRB | |
| Mandelic Acid SCHEMBL11409235 | 0.85 | LMNA (0.50) | ALDH1A1ALOX12LMNATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780358-A1 | A process for the resolution of 6-methoxy-alpha-methyl-2-naphthaleneacetic racemic acid into its enantiomers | FARCHEMIA S.r.l. (IT) | 1997-06-25 | — | — | EP | claimed |
| EP-0119463-B2 | PROCESS FOR THE SEPARATION OF ISOMERS OF SUBSTITUTED CYCLOPROPANECARBOXYLIC ACIDS | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-13 | — | — | EP | claimed |
| EP-0119463-B1 | PROCESS FOR THE SEPARATION OF ISOMERS OF SUBSTITUTED CYCLOPROPANECARBOXYLIC ACIDS | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1987-09-23 | — | — | EP | claimed |
| US-4599444-A | Process for the separation of isomeric cyclopropane-carboxylic acids | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1986-07-08 | — | — | US | claimed |
| EP-0119463-A1 | Process for the separation of isomers of substituted cyclopropanecarboxylic acids | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1984-09-26 | — | — | EP | claimed |
| US-4239912-A | SALT FORMATION | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | claimed |
| US-20260008787-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS INC (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4551577-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | Blossomhill Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024173453-A1 | HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-118043042-A | Conjugate comprising a covalent binding agent for targeting intracellular KRAS G12C proteins | 瑞择生物公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024015262-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| EP-2362775-B1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20120270902-A1 | N-substituted benzene sulfonamides | ELAN PHARMACEUTICALS, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-4259521-A | Process for resolving DL-mandelic acid | AMERICAN CYANAMID COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-4239912-A | SALT FORMATION | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4239912-A | SALT FORMATION | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4239912-A | SALT FORMATION | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| EP-0008833-A1 | Optically active derivatives of mercaptoisobutyric acid and a process for preparing them | Océ-Andeno B.V. (NL) | 1980-03-19 | — | — | EP | disclosed |
| US-4110286-A | Stable polyurethane latices, emulsifiable prepolymers therefor and methods of making the same | ALCOLAC INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4009201-A | PARTIALLY OR FULLY QUATERNIZED POLYAMINE ESTERS OF ACRYLIC ACIDS | ALCOLAC INC. (US) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008787-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | KRAS, NRAS, HRAS | ALDH1A1 2043/4885ALOX12 3389/4885SIGMAR1 700/4885 |
| US-20120270902-A1 | N-substituted benzene sulfonamides | PSEN1, PSEN2, BCHE | ALDH1A1 665/4885ALOX12 3140/4885SIGMAR1 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.