Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061307 | 1.00 | CASP6 (0.44) | CASP6CRHBPCRHR2ALDH1A1TDP1 | |
| SCHEMBL8061304 | 0.90 | CASP6 (0.41) | CASP6CRHBPCRHR2ALDH1A1TDP1 | |
| SCHEMBL8065636 | 0.81 | POLB (0.51) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL27986575 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL8065631 | 0.81 | POLB (0.51) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL1639309 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL8063665 | 0.80 | AKR1C3 (0.53) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL8063663 | 0.80 | AKR1C3 (0.53) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL27939312 | 0.78 | ALDH1A1 (0.63) | CASP6CRHBPCRHR2ALDH1A1TDP1 | |
| SCHEMBL27585698 | 0.78 | CASP6 (0.51) | CASP6CRHBPCRHR2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |