SCHEMBL8061402

SCHEMBL8061402

CC(=O)OCC1=CCOC1=O

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 1/20 0.41
GSTP1 P09211 6/20 0.38
NLRP3 Q96P20 1/20 0.37
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
GSTA2 P09210 1/20 0.33
IDH1 O75874 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1141683 0.72 ALDH1A1 (0.47) ALDH1A1CYP3A4GSTP1NLRP3CYP1A2
SCHEMBL21853584 0.69 GSTP1 (0.54) ALDH1A1CYP3A4GSTP1NLRP3CYP1A2
SCHEMBL12462176 0.69 ALDH1A1 (0.44) ALDH1A1CYP3A4GSTP1NLRP3CYP1A2
SCHEMBL23544215 0.67 ALDH1A1 (0.38) ALDH1A1CYP3A4GSTP1NLRP3GSTA2
SCHEMBL10824824 0.67 GSTP1 (0.68) ALDH1A1CYP3A4GSTP1NLRP3CYP2C19
SCHEMBL14855693 0.66
SCHEMBL3236430 0.66 CYP3A4 (0.42) ALDH1A1CYP3A4NLRP3CYP1A2CYP2C19
SCHEMBL8512166 0.66 CYP3A4 (0.42) ALDH1A1CYP3A4NLRP3CYP1A2CYP2C19
SCHEMBL21946527 0.65 GSTP1 (0.36) ALDH1A1CYP3A4GSTP1NLRP3GSTA2
SCHEMBL18196039 0.64 ALDH1A1 (0.43) ALDH1A1CYP3A4NLRP3CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed