SCHEMBL8512166

SCHEMBL8512166

CC(=O)OC[C]1C[CH]CO1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.42
ALDH1A1 P00352 4/20 0.40
NLRP3 Q96P20 2/20 0.35
NOTUM Q6P988 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA2 P00918 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14855693 0.67
SCHEMBL8061402 0.66 ALDH1A1 (0.43) CYP3A4ALDH1A1NLRP3HSD17B10CYP1A2
SCHEMBL23507799 0.63 CYP3A4 (0.46) CYP3A4ALDH1A1NLRP3NOTUMLMNA
SCHEMBL3236430 0.63 CYP3A4 (0.42) CYP3A4ALDH1A1NLRP3NOTUMLMNA
SCHEMBL18196039 0.62 ALDH1A1 (0.43) CYP3A4ALDH1A1NLRP3CYP1A2CYP2C19
SCHEMBL132773 0.62 ALDH1A1 (0.78) CYP3A4ALDH1A1LMNAHSD17B10CA2
SCHEMBL7167743 0.62 ALDH1A1 (0.52) CYP3A4ALDH1A1LMNAHSD17B10CA2
SCHEMBL3293016 0.62 ALDH1A1 (0.52) CYP3A4ALDH1A1NOTUMLMNAHSD17B10
SCHEMBL5666942 0.62 ALDH1A1 (0.64) CYP3A4ALDH1A1LMNAHSD17B10CA2
SCHEMBL23706582 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2643337-A1 PROCESS FOR THE PREPARATION OF (2R.3S)-2-(HYDROXYMETHYL) -5-METHOXYTETRAHYDROFURAN-3-OL AND ACETYLATED DERIVATIVES THEREOF, FREE OF PYRANOSE COMPOUNDS Johnson Matthey Public Limited Company (GB) 2013-10-02 EP claimed
WO-2012071508-A1 PROCESS FOR THE PREPARATION OF (2R.3S)-2-(HYDROXYMETHYL) -5-METHOXYTETRAHYDROFURAN-3-OL AND ACETYLATED DERIVATIVES THEREOF, FREE OF PYRANOSE COMPOUNDS JOHNSON MATTHEW PUBLIC LIMITED COMPANY (GB) 2012-05-31 WO claimed