Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | SELE | P16581 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CMA1 | P23946 | 4/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.40 |
| ▸ | PFKFB4 | Q16877 | 3/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788255 | 0.98 | L3MBTL1 (0.46) | L3MBTL1TDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL14620655 | 0.86 | L3MBTL1 (0.48) | L3MBTL1TDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL787547 | 0.85 | L3MBTL1 (0.50) | L3MBTL1TDP1KDM4ENPC1ALDH1A1 | |
| Potassium Ion SCHEMBL788254 | 0.84 | L3MBTL1 (0.46) | L3MBTL1TDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL787942 | 0.78 | CMA1 (0.51) | L3MBTL1CMA1PFKFB3PFKFB4NPSR1 | |
| SCHEMBL2226181 | 0.78 | NPSR1 (0.60) | L3MBTL1MAPTCMA1PFKFB3PFKFB4 | |
| SCHEMBL3946161 | 0.78 | PFKFB3 (0.53) | L3MBTL1CMA1PFKFB3PFKFB4NPSR1 | |
| Hydrochloric Acid SCHEMBL6712744 | 0.77 | NPSR1 (0.59) | L3MBTL1MAPTCMA1PFKFB3PFKFB4 | |
| SCHEMBL787895 | 0.76 | PFKFB3 (0.57) | L3MBTL1KDM4ECMA1PFKFB3PFKFB4 | |
| SCHEMBL14409805 | 0.75 | KDM4E (0.51) | L3MBTL1TDP1KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |
| US-9233946-B2 | Sulfonamide compounds | KANCERA AB (SE) | 2016-01-12 | — | — | US | disclosed |
| US-9233946-B2 | Sulfonamide compounds | KANCERA AB (SE) | 2016-01-12 | — | — | US | disclosed |
| US-20130172339-A1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2013-07-04 | — | — | US | disclosed |
| US-20130172339-A1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2013-07-04 | — | — | US | disclosed |
| WO-2012035171-A2 | NEW COMPOUNDS | KANCERA AB (SE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172339-A1 | SULFONAMIDE COMPOUNDS | SULT1A1, STS, ARSA | L3MBTL1 2627/4885TDP1 3961/4885KDM4E 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.