SCHEMBL8062

SCHEMBL8062

CC(O)OC(C)N1CCNCC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SIGMAR1 Q99720 1/20 0.30
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4754387 0.96 SMN1; SMN2 (0.39) SMN1; SMN2CHRM5CHRM3
SCHEMBL9081019 0.79 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL12650558 0.78 MEN1 (0.31) SMN1; SMN2MEN1KMT2AOPRD1
SCHEMBL8806059 0.77 SMN1; SMN2 (0.35) SMN1; SMN2MEN1KMT2A
SCHEMBL5731936 0.75 MEN1 (0.34) SMN1; SMN2CHRM5CHRM3MEN1KMT2A
SCHEMBL538775 0.75 MEN1 (0.34) SMN1; SMN2CHRM5CHRM3MEN1KMT2A
SCHEMBL1473655 0.75 MEN1 (0.34) SMN1; SMN2CHRM5CHRM3MEN1KMT2A
SCHEMBL11362053 0.74 ALDH1A1 (0.37) SMN1; SMN2MEN1KMT2A
SCHEMBL5617 0.74
SCHEMBL8373239 0.74 SMN1; SMN2 (0.38) SMN1; SMN2CHRM5CHRM3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389716-B2 Process for the synthesis of quetiapine F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 2013-03-05 US claimed
US-20110118460-A1 PROCESS FOR THE SYNTHESIS OF QUETIAPINE F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) 2011-05-19 US claimed
WO-2006027789-A1 PROCESS FOR PRODUCING 11-[4-[2-(2-HYDROXYETHOXY)ETHYL]-1-PIPERAZINYL]DIBENZO[b,f][1,4]THIAZEPINE AND A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF JUBILANT ORGANOSYS LIMITED (IN) 2006-03-16 WO claimed
EP-1102789-A1 MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM Menarini Ricerche S.p.A. (IT) 2001-05-30 EP claimed
WO-2000008046-A1 MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM MENARINI RICERCHE S.P.A. (IT) 2000-02-17 WO claimed
EP-0240228-B1 THIAZEPINE COMPOUNDS ICI AMERICAS INC. (US) 1990-11-07 EP claimed
US-12584083-B2 Surface treatment composition, surface treatment method, and method for producing semiconductor substrate FUJIMI INCORPORATED (JP) 2026-03-24 US disclosed
EP-4606929-A1 ETCHING SOLUTION, REPLENISHMENT SOLUTION, AND METHOD FOR FORMING COPPER WIRING MEC Company Ltd. (JP) 2025-08-27 EP disclosed
US-20240124810-A1 SURFACE TREATMENT COMPOSITION, SURFACE TREATMENT METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE FUJIMI INCORPORATED (JP) 2024-04-18 US disclosed
CN-117778117-A Surface treatment composition, surface treatment method, and method for manufacturing semiconductor substrate 福吉米株式会社 2024-03-29 CN disclosed
WO-2023140146-A1 POLISHING COMPOSITION, CONCENTRATED SOLUTION OF POLISHING COMPOSITION, AND POLISHING METHOD 株式会社フジミインコーポレーテッド 2023-07-27 WO disclosed
CN-113179590-A Etching solution, replenishment solution, and method for forming copper wiring MEC股份有限公司 2021-07-27 CN disclosed
CN-107208279-B Etching solution, replenishment solution, and method for forming copper wiring MEC股份有限公司 2021-03-26 CN disclosed
EP-0757670-A1 BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-02-12 EP disclosed
WO-1996041795-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-12-27 WO disclosed
WO-1995029152-A1 BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-11-02 WO disclosed
EP-0625997-A1 DIAMINOCARBONATE COMPOUNDS AND THEIR USE AS CATALYSTS. RWE DEA AG (DE) 1994-11-30 EP disclosed
WO-1993016124-A1 DIAMINOCARBONATE COMPOUNDS AND THEIR USE AS CATALYSTS RWE-DEA Aktiengesellschaft für Mineraloel und Chemie (DE) 1993-08-19 WO disclosed
US-4879288-A Novel dibenzothiazepine antipsychotic ICI AMERICAS INC. (US) 1989-11-07 US disclosed
US-4097597-A ANTISCHIZOPHRENICS ABBOTT LABORATORIES (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584083-B2 Surface treatment composition, surface treatment method, and method for producing semiconductor substrate PIEZO1, TYRO3, ACP1 SMN1; SMN2 1007/4885CHRM5 142/4885CHRM3 214/4885
US-20110118460-A1 PROCESS FOR THE SYNTHESIS OF QUETIAPINE CYP4F11, MAOB, CYP2F1 SMN1; SMN2 4797/4885CHRM5 1606/4885CHRM3 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.