SCHEMBL8062298

SCHEMBL8062298

C=CC[Si](CC=C)(CC=C)CCCOCC(O)CO

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.46
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5854880 0.82 USP2 (0.55) USP2HTT
SCHEMBL13880901 0.77 USP2 (0.58) USP2HTT
SCHEMBL3263381 0.77 USP2 (0.53) USP2CA1CA2CA7HTT
SCHEMBL13044735 0.75 USP2 (0.56) USP2HTT
SCHEMBL28790419 0.75 USP2 (0.56) USP2CA1CA2CA7HTT
SCHEMBL14962633 0.75 USP2 (0.56) USP2HTT
SCHEMBL8059780 0.75 USP2 (0.37) USP2
SCHEMBL23615815 0.74 USP2 (0.50) USP2CA1CA2CA7HTT
SCHEMBL5015551 0.74 USP2 (0.59) USP2CA1CA2CA7HTT
SCHEMBL30114778 0.74 USP2 (0.59) USP2CA1CA2CA7HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873189-B1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING & MFG (US) 2000-09-06 EP disclosed
US-5968652-A Silane coated particle 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-10-19 US disclosed
US-5876595-A OLEFINIC SILANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-02 US disclosed
EP-0873189-A1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-28 EP disclosed
US-5667674-A POLYCARBOSILANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
WO-1997025140-A1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-17 WO disclosed