SCHEMBL8059780

SCHEMBL8059780

C=CC[Si](CC=C)(CC=C)CCCCC(O)CO

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.37
THRB P10828 1/20 0.34
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL8058898 0.92 USP2 (0.36) USP2CYP3A4SMN1; SMN2
SCHEMBL16477666 0.83 ALDH1A1 (0.31) USP2CYP3A4SMN1; SMN2
SCHEMBL8062298 0.75 USP2 (0.46) USP2
SCHEMBL28438298 0.73 USP2 (0.59) USP2THRBCYP3A4SMN1; SMN2
SCHEMBL346306 0.73 USP2 (0.59) USP2THRBCYP3A4SMN1; SMN2
SCHEMBL16243897 0.73 LMNA (0.31)
SCHEMBL19368244 0.72 THRB (0.46) USP2THRBCYP3A4SMN1; SMN2
SCHEMBL8047506 0.72 TSHR (0.33)
SCHEMBL3114128 0.71 USP2 (0.62) USP2THRBCYP3A4SMN1; SMN2
SCHEMBL4457448 0.71 USP2 (0.62) USP2THRBCYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873189-B1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING & MFG (US) 2000-09-06 EP disclosed
US-5968652-A Silane coated particle 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-10-19 US disclosed
US-5876595-A OLEFINIC SILANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-02 US disclosed
EP-0873189-A1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-28 EP disclosed
US-5667674-A POLYCARBOSILANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
WO-1997025140-A1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-17 WO disclosed