Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13158697 | 0.90 | CYP2A6 (0.73) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 | |
| SCHEMBL13158692 | 0.90 | CYP2A6 (0.73) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 | |
| SCHEMBL10068137 | 0.90 | ALDH1A1 (0.59) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 | |
| SCHEMBL3340810 | 0.90 | CYP2A6 (0.73) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 | |
| SCHEMBL339173 | 0.90 | CYP2A6 (0.73) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 | |
| SCHEMBL20546774 | 0.88 | CYP2A6 (0.76) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 | |
| SCHEMBL10068360 | 0.88 | CYP2A6 (0.53) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 | |
| SCHEMBL6004796 | 0.86 | ALDH1A1 (0.54) | CYP2A6ALDH1A1MAPK1TDP1CYP3A4 | |
| SCHEMBL1334409 | 0.86 | ALDH1A1 (0.54) | CYP2A6ALDH1A1MAPK1TDP1CYP3A4 | |
| SCHEMBL13805764 | 0.85 | CYP2A6 (0.64) | CYP2A6ALDH1A1ALDH1A3ALDH3A1CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036295-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2012-03-22 | — | — | WO | disclosed |