Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064414 | 0.86 | TAS2R31 (0.53) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL12067028 | 0.83 | MAOB (0.69) | CYP19A1MAOBABCB1ARABCG2 | |
| SCHEMBL23778062 | 0.82 | PDE4B (0.46) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL8069162 | 0.82 | ALDH1A1 (0.65) | PDE4DCYP19A1ABCG2 | |
| SCHEMBL8069101 | 0.81 | MAOB (0.47) | CYP19A1MAOBABCB1ARABCG2 | |
| SCHEMBL23778017 | 0.81 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4DTDP1 | |
| SCHEMBL28320429 | 0.79 | ROR1 (0.68) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL15756384 | 0.77 | PTPN1 (0.84) | PTPN1CYP19A1MAOB | |
| SCHEMBL11430072 | 0.76 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL7030024 | 0.75 | CYP19A1 (0.80) | PTPN1CYP19A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |