Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 8/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070235 | 0.99 | NPY1R (0.36) | NPY1RFOLH1CNR1NPY4RHTT | |
| SCHEMBL8076494 | 0.95 | CNR1 (0.38) | NPY1RFOLH1CNR1NPY5R | |
| SCHEMBL8059172 | 0.94 | ATM (0.38) | NPY1RFOLH1CNR1 | |
| SCHEMBL8071280 | 0.93 | ATM (0.40) | FOLH1CNR1 | |
| SCHEMBL8069648 | 0.89 | FOLH1 (0.44) | FOLH1CNR1HTTSLC1A3SLC1A1 | |
| SCHEMBL8068008 | 0.88 | MTNR1A (0.37) | FOLH1 | |
| SCHEMBL8069819 | 0.85 | MMP2 (0.45) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL7600478 | 0.85 | FOLH1 (0.38) | NPY1RFOLH1CNR1HTTSLC1A3 | |
| SCHEMBL7597915 | 0.85 | FOLH1 (0.38) | NPY1RFOLH1CNR1HTTSLC1A3 | |
| SCHEMBL8070175 | 0.84 | FOLH1 (0.42) | FOLH1CNR1HTTSLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |