Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979223 | 0.97 | NPC1 (0.45) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL7965830 | 0.95 | NPC1 (0.46) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL8060866 | 0.94 | NPC1 (0.47) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL7977788 | 0.92 | NPC1 (0.43) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL7965797 | 0.91 | NPC1 (0.44) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL7976273 | 0.89 | RHOC (0.47) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL8060909 | 0.88 | NPC1 (0.52) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL7977366 | 0.88 | NPC1 (0.48) | NPC1KMT2AL3MBTL1RHOCRHOA | |
| SCHEMBL8050888 | 0.87 | NPC1 (0.47) | NPC1KMT2ARHOCRHOAHPGD | |
| SCHEMBL7975921 | 0.86 | RHOC (0.44) | NPC1KMT2AL3MBTL1RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-6028100-A | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-22 | — | — | US | disclosed |
| US-5952386-A | EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-14 | — | — | US | disclosed |
| WO-1996033160-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-24 | — | — | WO | disclosed |