Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.41 |
| ▸ | PTGIR | P43119 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953106 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL7962995 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL7948483 | 0.83 | PSMB8 (0.56) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL4138516 | 0.83 | PSMB5 (0.53) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL5504988 | 0.82 | TAAR1 (0.53) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL4136821 | 0.82 | MEN1 (0.46) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL4130976 | 0.82 | PSMB8 (0.46) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL5234354 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10671160 | 0.82 | PSMB8 (0.55) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL3142808 | 0.82 | PSMB5 (0.52) | ALDH1A1LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037411-A9 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012037411-A2 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |