Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.83 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.72 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.72 |
| ▸ | CREB1 | P16220 | 1/20 | 0.70 |
| ▸ | FLT3 | P36888 | 3/20 | 0.65 |
| ▸ | AURKA | O14965 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | GFER | P55789 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069068 | 0.92 | HDAC6 (0.74) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| SCHEMBL8064420 | 0.91 | HDAC6 (0.80) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| Eupatilin SCHEMBL29926197 | 0.91 | HDAC6 (1.00) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| Eupatilin SCHEMBL29568655 | 0.91 | HDAC6 (1.00) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| Eupatilin SCHEMBL1033509 | 0.91 | HDAC6 (1.00) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| SCHEMBL8052889 | 0.90 | HDAC6 (0.78) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| SCHEMBL8064417 | 0.89 | HDAC6 (0.77) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| SCHEMBL8052881 | 0.87 | CYP1B1 (0.67) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| SCHEMBL3131502 | 0.85 | CYP1B1 (1.00) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 | |
| SCHEMBL34468184 | 0.85 | CYP1B1 (1.00) | HDAC6CYP1B1CYP1A1OPRD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |