Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 4/20 | 1.00 |
| ▸ | CYP1A1 | P04798 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 1/20 | 1.00 |
| ▸ | FLT3 | P36888 | 2/20 | 0.84 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.84 |
| ▸ | AURKA | O14965 | 1/20 | 0.84 |
| ▸ | KDR | P35968 | 1/20 | 0.84 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.81 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.81 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468184 | 1.00 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| SCHEMBL31238120 | 1.00 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Sinensetin SCHEMBL7020909 | 0.98 | CYP1B1 (0.95) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Eupatilin SCHEMBL29568655 | 0.91 | HDAC6 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Eupatilin SCHEMBL1033509 | 0.91 | HDAC6 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Eupatorin SCHEMBL555597 | 0.91 | CYP1A1 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Eupatorin SCHEMBL29386042 | 0.91 | CYP1A1 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Eupatilin SCHEMBL29926197 | 0.91 | HDAC6 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Eupatorin SCHEMBL30334912 | 0.91 | CYP1A1 (1.00) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 | |
| Cirsileneol SCHEMBL2045672 | 0.91 | HSD17B2 (0.86) | CYP1B1CYP1A1CYP1A2OPRD1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | DEEPSENSE BIOTECHNOLOGIES INC (US) | 2026-04-30 | — | — | US | claimed |
| CN-119453207-A | Submicron antibacterial material, preparation method of medical material doped with submicron antibacterial material and antibacterial catheter | 广东广纳特飞科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-116953125-A | Separation method and content determination method of chemical components in Murraya paniculata | 华润三九医药股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-114984103-B | Orange peel extract and preparation method and application thereof | 赣南师范大学 | 2023-10-03 | — | — | CN | claimed |
| CN-115886131-A | Feed additive prepared from citrus leaf extract and preparation method thereof | 成都农业科技职业学院 | 2023-04-04 | — | — | CN | claimed |
| CN-114984103-A | Orange peel extract and preparation method and application thereof | 赣南师范大学 | 2022-09-02 | — | — | CN | claimed |
| CN-109633039-B | Method for detecting hydroxyl polymethoxylated flavone compound and metabolite thereof in biological sample | 北京中医药大学 | 2021-09-10 | — | — | CN | claimed |
| US-10682332-B2 | Method for treating melanoma | Huanggang normal university (CN) | 2020-06-16 | — | — | US | claimed |
| US-20190046498-A1 | METHOD FOR TREATING MELANOMA | HENAN UNIVERSITY (CN) | 2019-02-14 | — | — | US | claimed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| WO-2013021258-A1 | ANTI-TUBERCULAR COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-02-14 | — | — | WO | claimed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | claimed |
| WO-2006132879-A2 | SOFT GEL CAPSULES CONTAINING POLYMETHOXYLATED FLAVONES AND PALM OIL TOCOTRIENOLS | SOFT GEL TECHNOLOGIES, INC. (US) | 2006-12-14 | — | — | WO | claimed |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | THE CIT GROUP/CREDIT FINANCE, INC. | 2006-01-05 | — | — | US | claimed |
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | SOFT GEL TECHNOLOGIES, INC. | 2005-11-10 | — | — | US | claimed |
| EP-1278417-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK Synergie (CA) | 2003-01-29 | — | — | EP | claimed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | claimed |
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | DEEPSENSE BIOTECHNOLOGIES INC (US) | 2026-04-30 | — | — | US | disclosed |
| WO-2000019998-A1 | COMPOSITIONS AND METHODS OF INHIBITING NEOPLASTIC DISEASES WITH COMPOUNDS RELATED TO LIMOCITRIN AND 5-DESMETHYL SINENSETIN | KGK SYNERGIZE (CA) | 2000-04-13 | — | — | WO | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, CCNE2, PTGES | CYP1B1 3090/4885CYP1A1 793/4885CYP1A2 484/4885 |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, PLA2G10, GSTO1 | CYP1B1 2316/4885CYP1A1 660/4885CYP1A2 409/4885 |
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | PLIN3, PNLIP, FABP2 | CYP1B1 341/4885CYP1A1 119/4885CYP1A2 133/4885 |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | PLIN5, FANCF, COXFA4 | CYP1B1 264/4885CYP1A1 175/4885CYP1A2 156/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | CYP1B1 264/4885CYP1A1 175/4885CYP1A2 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.