Eupatilin

Eupatilin

SCHEMBL29568655

COc1ccc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 1.00
HSD17B2 P37059 1/20 0.86
TAS2R31 P59538 1/20 0.86
CYP1B1 Q16678 3/20 0.84
CYP1A1 P04798 2/20 0.84
OPRD1 P41143 2/20 0.84
CYP1A2 P05177 1/20 0.84
MAPT P10636 5/20 0.78
MEN1 O00255 4/20 0.78
KMT2A Q03164 4/20 0.78
POLB P06746 4/20 0.78
NPC1 O15118 3/20 0.78
GFER P55789 2/20 0.78
KDM4E B2RXH2 2/20 0.78
AMY1A P0DUB6 1/20 0.78
GAA P10253 1/20 0.78
THRB P10828 1/20 0.78
APEX1 P27695 1/20 0.78
RECQL P46063 1/20 0.78
BLM P54132 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eupatilin SCHEMBL1033509 1.00 HDAC6 (1.00) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
Eupatilin SCHEMBL29926197 1.00 HDAC6 (1.00) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
SCHEMBL8069022 0.93 FLT3 (0.86) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
SCHEMBL30799172 0.93 FLT3 (0.86) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
Jaceosidine SCHEMBL29926544 0.93 HSD17B2 (1.00) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
Jaceosidine SCHEMBL3960077 0.93 HSD17B2 (1.00) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
SCHEMBL3131502 0.91 CYP1B1 (1.00) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
SCHEMBL34468184 0.91 CYP1B1 (1.00) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
SCHEMBL31238120 0.91 CYP1B1 (1.00) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1
SCHEMBL7606758 0.91 HDAC6 (0.84) HDAC6HSD17B2TAS2R31CYP1B1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114432296-A Application of eupatilin in preparation of product for resisting skin photodamage 中国农业大学 2022-05-06 CN disclosed