Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921062 | 0.75 | LMNA (0.35) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL677810 | 0.71 | LMNA (0.32) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29036726 | 0.68 | LMNA (0.32) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL868896 | 0.68 | LMNA (0.35) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28165020 | 0.68 | — | — | |
| SCHEMBL868897 | 0.67 | CYP2D6 (0.30) | — | |
| SCHEMBL14773437 | 0.65 | — | — | |
| SCHEMBL29009187 | 0.65 | — | — | |
| SCHEMBL228835 | 0.64 | ALOX15 (0.34) | LMNA | |
| SCHEMBL1539596 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684980-B1 | IMPROVED AQUEOUS FUNCTIONAL FLUID | CINCINNATI MILACRON INC (US) | 2000-05-31 | — | — | EP | disclosed |
| CN-1047614-C | Aqueous functional fluid having improved resistance to micro-organisms | CINCINNATI MILACRON INC (US) | 1999-12-22 | — | — | CN | disclosed |
| EP-0684980-A4 | IMPROVED AQUEOUS FUNCTIONAL FLUID. | CINCINNATI MILACRON INC (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5512191-A | NITROGEN BEARING COMPOUND, HALOALKYNYLALKYL CARBAMATE | CINCINNATI MILACRON INC. (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0684980-A1 | IMPROVED AQUEOUS FUNCTIONAL FLUID | CINCINNATI MILACRON INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| CN-1111674-A | Aqueous functional fluid having improved resistance to micro-organisms | CINCINNATI MILACRON INC (US) | 1995-11-15 | — | — | CN | disclosed |
| WO-1995017491-A1 | IMPROVED AQUEOUS FUNCTIONAL FLUID | CINCINNATI MILACRON INC. (US) | 1995-06-29 | — | — | WO | disclosed |