Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.47 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 5/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920444 | 0.80 | CNR1 (0.60) | KMT2AMEN1 | |
| SCHEMBL4547159 | 0.80 | LMNA (0.50) | LMNATBK1IKBKESYKKAT6A | |
| SCHEMBL31368250 | 0.79 | LMNA (0.49) | LMNATBK1SYKKAT6AKMT2A | |
| SCHEMBL31173853 | 0.78 | LMNA (0.56) | LMNATBK1KAT6ASIRT2SIRT1 | |
| SCHEMBL2161445 | 0.78 | LMNA (0.56) | LMNATBK1KAT6ASIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL1117908 | 0.78 | LMNA (0.49) | LMNATBK1IKBKESYKKAT6A | |
| SCHEMBL5537719 | 0.77 | LMNA (0.59) | LMNATBK1SYKKAT6AKMT2A | |
| SCHEMBL27658507 | 0.76 | AOC2 (0.53) | — | |
| SCHEMBL27926580 | 0.76 | LMNA (0.47) | LMNATBK1SYKKAT6AKMT2A | |
| SCHEMBL4948621 | 0.76 | LMNA (0.47) | LMNASYKKAT6AKMT2AERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |