Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183024 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL7197746 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9255478 | 0.85 | CYP3A4 (0.39) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9185141 | 0.85 | ALDH1A1 (0.39) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9186491 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9185734 | 0.83 | MAPT (0.41) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9185698 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9185749 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9179828 | 0.82 | CYP3A4 (0.47) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL9185070 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000119542-A | PRODUCTION OF SYMMETRIC TYPE AZAPHTHALIDE-BASED COMPOUND | YAMAMOTO CHEM INC | 2000-04-25 | — | — | JP | disclosed |