Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186491 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9184164 | 0.87 | CYP3A4 (0.47) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9180534 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9263278 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9185723 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9183024 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9180594 | 0.85 | HPGD (0.49) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9184168 | 0.85 | CYP3A4 (0.45) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 | |
| SCHEMBL9184143 | 0.83 | GHSR (0.38) | ALDH1A1TDP1HPGDCYP3A4KMT2A | |
| SCHEMBL9320143 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TDP1HPGDCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401699-A | Thermosensitive elements with color developers, fluoran derivatives and azaphthalides | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |