SCHEMBL8064762

SCHEMBL8064762

CC(C)(c1cc(Cl)c(O)c(Cl)c1Cl)c1cc(Cl)c(O)c(Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.52
TSHR P16473 6/20 0.52
HPGD P15428 6/20 0.52
MAPK1 P28482 2/20 0.52
SMN1; SMN2 Q16637 5/20 0.40
HIF1A Q16665 4/20 0.40
CYP2C19 P33261 3/20 0.40
CYP2C9 P11712 2/20 0.40
TP53 P04637 1/20 0.40
ALDH1A1 P00352 5/20 0.39
CYP3A4 P08684 4/20 0.39
RECQL P46063 3/20 0.39
TTR P02766 2/20 0.39
CASP1 P29466 2/20 0.39
THRB P10828 2/20 0.36
ALOX15 P16050 4/20 0.35
ALOX12 P18054 3/20 0.35
CYP1A2 P05177 3/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6885318 0.86 HSD17B10 (0.46) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL11390941 0.83 HPGD (0.38) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL10695590 0.77 HSD17B10 (0.52) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL8956997 0.74 HSD17B10 (0.39) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
Bisphenol A SCHEMBL6049372 0.74 ESR1 (0.53) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL24946528 0.73 SMN1; SMN2 (0.53) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL11672979 0.73 HSD17B10 (0.36) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL23542373 0.73 SMN1; SMN2 (0.48) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL698785 0.73 HSD17B10 (0.56) HSD17B10TSHRHPGDMAPK1SMN1; SMN2
SCHEMBL54380 0.69 HSD17B10 (1.00) HSD17B10TSHRHPGDMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US claimed
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US disclosed
US-6031061-A Bis (triaklyltrimellitic anhydride) derivative and polyesterimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-29 US disclosed
EP-0029242-B1 PROCESS FOR PRODUCING A MIXED HALOGEN-CONTAINING POLYCARBONATE RESIN MITSUBISHI KASEI CORPORATION (JP) 1985-04-17 EP disclosed
US-4323663-A Process for producing a halogen-containing polycarbonate resin MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1982-04-06 US disclosed