Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698002 | 0.83 | HSD17B10 (0.43) | HSD17B10TSHRHPGDMAPK1HTR3E | |
| SCHEMBL1768795 | 0.78 | CYP3A4 (0.50) | HSD17B10TSHRHPGDMAPK1HTR3E | |
| SCHEMBL8064762 | 0.77 | HSD17B10 (0.52) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL10707497 | 0.74 | HPGD (0.48) | HSD17B10TSHRHPGDMAPK1HTR3E | |
| SCHEMBL10695573 | 0.74 | HTR3E (0.37) | HSD17B10TSHRHPGDMAPK1HTR3E | |
| SCHEMBL7855792 | 0.73 | TP53 (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10616182 | 0.73 | ALDH1A1 (0.39) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10482195 | 0.73 | KDR (0.35) | TSHRHPGDHTR3EHTR3BHTR3A | |
| SCHEMBL10825784 | 0.73 | HTR3E (0.43) | HSD17B10TSHRHPGDMAPK1HTR3E | |
| SCHEMBL8830349 | 0.72 | NOTUM (0.35) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |